| United States Patent Application |
20030147970
|
| Kind Code
|
A1
|
|
Newman, Ira Jay
; et al.
|
August 7, 2003
|
Ionic silver complex
Abstract
The invention relates to a substantially non-colloidal solution made by
combining ingredients comprising (a) water; (b) a source of free silver
ions; and (c) a substantially non-toxic, substantially thiol-free,
substantially water-soluble complexing agent.
| Inventors: |
Newman, Ira Jay; (Fort Lauderdale, FL)
; Washburn, David; (West Palm Beach, FL)
|
| Correspondence Name and Address:
|
NEEDLE & ROSENBERG P C
127 PEACHTREE STREET N E
ATLANTA
GA
30303-1811
US
|
| Serial No.:
|
383345 |
| Series Code:
|
10
|
| Filed:
|
March 7, 2003 |
| U.S. Current Class: |
424/618 |
| U.S. Class at Publication: |
424/618 |
| Intern'l Class: |
A61K 033/38 |
Claims
1. A substantially non-colloidal solution made by combining ingredients
comprising: (a) water; (b) a source of free silver ions; and (c) a
substantially non-toxic, substantially thiol-free, substantially
water-soluble complexing agent.
2. The substantially non-colloidal solution of claim 1, wherein the
non-colloidal solution possesses less than about ten weight percent of
free silver based on the weight of total silver.
3. The substantially non-colloidal solution of claim 2, wherein the
non-colloidal solution possesses less than about one weight percent of
free silver based the weight of total silver.
4. The substantially non-colloidal solution of claim 3, wherein the
non-colloidal solution possesses less than about one-tenth of a percent
by weight of free silver based on the weight of total silver.
5. The substantially non-colloidal solution of claim 1, wherein the
non-colloidal solution possesses greater than about twenty parts of total
silver per million parts of the non-colloidal solution.
6. The substantially non-colloidal solution of claim 5, wherein the
non-colloidal solution possesses greater than about fifty parts of total
silver per million parts of the non-colloidal solution.
7. The substantially non-colloidal solution of claim 6, wherein the
non-colloidal solution possesses greater than or equal to about one
hundred parts of total silver per million parts of the non-colloidal
solution.
8. The substantially non-colloidal solution of claim 1, wherein the source
of free silver ions comprises silver oxide, trisilver citrate, or silver
acetate.
9. The substantially non-colloidal solution of claim 8, wherein the source
of free silver ions comprises silver oxide.
10. The substantially non-colloidal solution of claim 1, wherein the
substantially non-toxic, substantially thiol-free, substantially
water-soluble complexing agent comprises a carboxylic acid, or a primary,
secondary or tertiary amine.
11. The substantially non-colloidal solution of claim 10, wherein the
substantially non-toxic, substantially thiol-free, substantially
water-soluble complexing agent comprises amino acids or hydroxy acids.
12. The substantially non-colloidal solution of claim 11, wherein the
amino acids comprise glycine, alanine, valine, leucine, isoleucine,
methionine, proline, phenylalanine, tryptophan, serine, threonine,
tyrosine, asparagine, glutamine, aspartic acid, glutamic acid, lysine,
arginine, or histidine.
13. The substantially non-colloidal solution of claim 12, wherein the
hydroxy acids comprise glycolic acid, lactic acid, malic acid, tartaric
acid, citric acid, or mandelic acid.
14. The substantially non-colloidal solution of claim 13; wherein the
citric acid is dibasic citrate.
15. The substantially non-colloidal solution of claim 1, wherein the free
silver ions are present in the substantially non-colloidal solution in an
anti-microbially effective amount.
16. The substantially non-colloidal solution of claim 1, wherein the
ingredients further comprise a source of counter-ions.
17. The substantially non-colloidal solution of claim 1, wherein the
source of counter-ions comprises potassium ions, or calcium ions.
Description
CROSS-REFERENCE TO RELATED APPLICATIONS
[0001] This application is a continuation of application Ser. No.
10/175,260, filed on Jun. 18, 2002, which is a continuation of
application Ser. No. 09/796,242, filed on Feb. 28, 2001, which is a
continuation of application Ser. No. 09/435,158, filed Nov. 5, 1999,
which claims the benefit of U.S. Provisional Application No. 60/107,710,
filed Nov. 9, 1998. Each of the applications is incorporated by reference
in their entireties.
BACKGROUND OF THE INVENTION
[0002] 1. Field of the Invention
[0003] This invention relates to solutions including complexed ionic
silver. More particularly, it relates to solutions including complexed
ionic silver wherein the solutions convey health benefits through their
use or application.
[0004] 2. Description of Related Art
[0005] Silver has been known to act antimicrobially as an agent in and on
the body of humans as well as other animals, and to be relatively
non-toxic to mammalian cells when used in the minute quantities needed to
be antimicrobially effective. The most effective form of silver for
antimicrobial use is as ions in solution. Silver ions have been shown in
the past to have antibacterial, antiviral and antifungal qualities, and
to contribute directly to the regeneration of tissue. While the exact
method by which silver ions perform these functions is not known, it is
believed that they may (1) disrupt the respiratory functions, or (2)
disrupt membrane functionality of single-celled microorganisms, or (3)
link to the cell's DNA and disrupt cell functions. It is not
conventionally understood why silver ions appear to some to be effective
at regenerating tissue, which apparently involves more than acting as an
antimicrobial agent.
[0006] During recent years, ionic silver substances have been undergoing a
substantial resurgence in popularity, and are increasingly regarded as a
reasonably safe and effective antimicrobial agent. Silver ion substances
are increasingly being used in medical applications as well as by those
seeking a natural alternative to traditional antibiotic medications.
Ionic silver substances are being used in topical dressings to treat
wounds and to prevent and treat infections. They are also being used for
water supply sanitation for public utilities, for pharmaceutical
equipment sanitation, and for killing germs including the germ that
causes Legionnaires' Disease in the water systems of hospitals. Tooth
brushes are now being introduced that release silver ions in order to
fight oral bacteria.
[0007] However, delivering silver ions for utilization in or on the body
is a challenge because silver ions are electrically attracted to a host
of substances in and on the body, resulting in the silver ions rapidly
forming complexes or compounds wherein the ion is no longer available to
perform the appropriate antimicrobial function. A controlled, gradual
release of silver ions is desirable for achieving appropriate use of
silver ions in or on the body in order to offset this phenomenon, and is
especially challenging for antimicrobial use of silver ions internally
such as upon oral ingestion. If free silver, defined as silver ions which
are not part of a complex or compound, and are therefore biologically
available, are delivered at once to the body, there is only opportunity
for them to perform the antimicrobial function for an instant where they
make contact with the body or the oral tissue before being rendered
inactive.
[0008] The desirable characteristics of an antimicrobial ionic silver
formulation are that it gradually releases its silver content as free
silver ions upon ingestion or upon topical application in a manner that
is slow enough to sustain the antimicrobial functionality for a
sufficient period of time while also being rapid enough to be
substantially effective, that it facilitate mobility of the silver
through the body upon oral ingestion prior to gradually releasing its
silver content as available free silver ions, and that it be nontoxic to
the body.
[0009] Topical applications of ionic silver do not require a controlled,
gradual release of silver ions to the degree that internal, oral
ingestion applications require it because there is a lower presence of
agents with which the silver ions can bind up and form complexes or
compounds upon topical exposure as compared with ingestion for internal
use. At least one product has been recently introduced that consists of a
film dressing impregnated with a complex that gradually releases silver
ions upon exposure to the body's chemistry.
[0010] Previously, some silver-containing chemical substances, such as
silver nitrate, have been utilized in an effort to gain the antimicrobial
benefits of silver ions, but these substances have proven minimally
effective in or on the body because they immediately deliver all of their
silver content as free silver ions. Some such substances, such as silver
nitrate, are undesirably toxic to the human body when administered in
typical doses.
[0011]
Colloidal silver is a substance which has been in use for about a
hundred years. It provides a reasonable degree of controlled release and
mobility of silver ions in and on the body.
Colloidal silver is
apparently made up of minute particles of silver, associated with silver
ions that comprise a small percentage of such particles. The mass of
these particles provide a degree of controlled, gradual release of silver
ions as the body's chemistry breaks down these particles.
[0012] However, the electrolysis process that is used to make most
colloidal silver has substantial limitations and does not enable adequate
consistency in terms of parts per million (PPM) of silver relative to the
total solution by molar weight, particle size, or percentage of ions, for
most desired applications. Additionally, purity of the substance is
typically limited because electrolytes must usually be added to the water
during the production method, the most common of which is sodium. Oxides
typically form during production, often resulting in an undesirable
yellow or brown color. Moreover, the potency of most electrically
produced
colloidal silver is inherently limited. After a concentration of
approximately 5 PPM of silver (in some cases up to approximately 20 PPM
of silver) is reached, the production method typically fails to continue
yielding electron-deficient silver particles. The particles formed after
such a concentration is reached are typically not capable of performing
antimicrobial functions as do the particles that are initially produced
prior to reaching this approximate level of total silver concentration
(the aggregate of the complexed silver and the free, available silver in
the water-based solution).
[0013] The term colloidal means "something suspended in a dissimilar
medium," and shelf life is, therefore, inherently limited because the
colloidal silver particles gradually settle out of the water. Colloidal
particles are not dissolved in the water medium; they are not in
solution. The suspension is a result of, for example, Brownian motion
which is insufficient to keep the particles from settling out over time.
Some
colloidal silver substances have stabilizing agents such as proteins
added to the formula, but these tend to further hinder the availability
of the silver ions to the body. What is therefore needed are compositions
comprising silver ions, and methods of making and using such
compositions, that address the aforementioned problems.
SUMMARY OF THE INVENTION
[0014] In an aspect, the invention relates to a substantially
non-colloidal solution made by combining ingredients comprising (a)
water; (b) a source of free silver ions; and (c) a substantially
non-toxic, substantially thiol-free, substantially water-soluble
complexing agent.
DETAILED DESCRIPTION
[0015] The inventors have unexpectedly discovered that a substantially
non-colloidal solution made by combining ingredients comprising (a)
water; (b) a source of free silver ions; and (c) a substantially
non-toxic, substantially thiol-free, substantially water-soluble
complexing agent overcomes many of the limitations inherent in the
aforementioned forms of ionic silver substances and has wide application
in and on the body.
[0016] The inventive, substantially non-colloidal solution provides silver
ion concentrations well above those typically provided by
colloidal
silver products. The production method provides a typically consistent
formulation. The inventive formulation is highly stable, has many years
of shelf life, and maintains its consistency and structure under a wide
range of environmental conditions. Substantially wide concentration
ranges of complexed silver are attainable without significantly
compromising the desirable characteristics of the product. The
composition of the invention efficiently provides for substantial
mobility of the silver complex through the body and for controlled
decomplexing of its silver content, whereupon it gradually releases
silver as available free silver ions, upon introduction of the product to
the body's chemistry internally through oral ingestion or upon topical
application.
[0017] Further, the inventive, substantially non-colloidal solution is
relatively nontoxic to the human body at typical doses.
[0018] The inventive substantially non-colloidal solutions are made from
ingredients comprising water, a source of free silver ions; and a
substantially non-toxic, substantially thiol-free, substantially
water-soluble complexing agent.
[0019] Water usable in the practice of this invention should be relatively
pure. Suitable types of water include: deionized water, distilled water,
reverse osmosis filtered water, reagent grade water and USP grade water
suitable for use in pharmaceuticals. The water is desirably substantially
free of contaminants, such as parasites, pathogens, chemical
contaminants, and particulate contamination.
[0020] The source of silver ions may be virtually any compound or complex
which includes silver ions as a constituent, from which those silver ions
can be obtained in order to be complexed with the recited complexing
agent or to become free silver ions as part of the inventive solution.
Sources of silver ions comprise silver oxide, trisilver citrate, silver
acetate, water soluble silver salts or any number of other sources of
silver without departing from the scope of the invention. In a preferable
embodiment, the source of silver ions is silver oxide (AgO). On
complexing, silver oxide eliminates a superfluous counter ion, hydroxide,
which is innocuous since hydroxide is already present in the solution.
[0021] The substantially non-toxic, substantially thiol-free,
substantially water-soluble complexing agent serves primarily to provide
a "controlled release" of biologically active silver ions. In the context
of the invention, complexing agent may be taken to mean an ionic material
with which silver ions are complexed in such a manner that the complexing
agent forms a weak bond with the silver ions wherein the missing electron
position which is a characteristic of the silver ion is filled by an
electron of the complexing agent. The substantially non-toxic,
substantially thiol-free, substantially water-soluble complexing agent
may comprise a carboxylic acid, or a primary, secondary or tertiary
amine. In the context of this invention, substantially non-toxic may be
taken to mean that the recited complexing agent, when present in the
inventive solution in usual amounts according to the invention, and when
administered as part of the inventive solution in usual dosage amounts of
the inventive solution, creates little or no toxic effects in a host to
which the inventive solution is administered. In an embodiment, the
substantially non-toxic, substantially thiol-free, substantially
water-soluble complexing agent comprises amino acids or hydroxy acids. In
a preferable embodiment, the amino acids comprise glycine, alanine,
valine, leucine, isoleucine, methionine, proline, phenylalanine,
tryptophan, serine, threonine, tyrosine, asparagine, glutamine, aspartic
acid, glutamic acid, lysine, arginine, or histidine. In another
preferable embodiment, the hydroxy acids comprise glycolic acid, lactic
acid, malic acid, tartaric acid, citric acid, or mandelic acid. In a more
preferable embodiment, the citric acid comprises dibasic citrate.
Citrate, a key constituent of the metabolic system, is aggressively drawn
to the cells throughout the body and provides an efficient delivery
system for spreading the silver through the body before decomplexing
takes place and the silver is gradually released as available free silver
ions. Also useful are acetic acid; certain crown ethers; primary,
secondary or tertiary amines, such as ethanolamine, and other
conventionally known substantially non-toxic, substantially thiol-free,
substantially watersoluble complexing agents.
[0022] In an embodiment, the inventive substantially non-colloidal
solution possesses greater than about twenty parts of silver per million
parts of the non-colloidal solution. In the context of this invention,
PPM is defined as parts of total silver to 1,000,000 parts of the total
solution including the water base and all substances contained in it by
weight. In another embodiment, the substantially non-colloidal solution
possesses greater than about fifty parts of total silver per million
parts of the non-colloidal solution. In a more preferable embodiment, the
substantially non-colloidal solution posesses greater than or equal to
about one hundred parts of total silver per million parts of the
non-colloidal solution. Higher parts per million of total silver are
desirable, as biological effectiveness increases as PPM free silver
increases.
[0023] 100 PPM of silver is a desirable level for the total concentration
of silver because it provides a highly effective concentration of silver
yet the concentration is low enough to facilitate ease of measuring and
dispensing the small dosages appropriate for small children and small
animals. However, the amount of silver can vary substantially, within
solubility limits, without departing from the scope of the invention, as
long as the other elements are varied in relative proportion to the
silver. In another embodiment, the inventive solution may be comprised of
as little as about 10 PPM of silver or as much as about 10,000 PPM of
silver without departing from the scope of the invention.
[0024] In an aspect of the invention, counter ions may be utilized. Such
counter ions may be used to balance the charge present in the recited
complexing agent, if necessary. Sources for counter ions suitable for use
in this invention include those conventionally known sources of counter
ions. Any suitable source of counter ions may be used where the
complexing agent is such that a counter ion is required to maintain the
electrical stability of the silver complex, so long as the counter ion
used does not compete with the silver for the complexing agent. In a
preferable embodiment, the source of counter-ions comprises potassium
ions, or calcium ions.
[0025] In an aspect of the invention, the inventive non-colloidal solution
possesses less than about ten weight percent of free silver based on the
weight of total silver. In an aspect of the invention, the non-colloidal
solution possesses less than about one weight percent of free silver
based on the weight of total silver. In an aspect of the invention, the
non-colloidal solution possesses less than about one-tenth of a weight
percent of free silver based on the weight of total silver. A relatively
low amount of free silver as compared to total silver (including non-free
silver or complexed silver), is retained in a non-reacted state in the
inventive solution, until released over time by the equilibrium driving
force. This controlled release aspect of the inventive formulation is
desirable, as activity is retained over time.
[0026] The preferred embodiment of the invention, containing a complex of
citrate and silver with potassium as a counter ion, may include the
following complex of ions in a solution of relatively pure water:
AgCOOCH.sub.2COHCOOCH.sub.2COOH.sup.-(aq) Ag.sup.+(aq)+COOCH.sub.2COHCOOCH-
.sub.2COOH.sup.2-(aq)
[0027] In a preferable embodiment the inventive solution may be made by
mixing silver oxide, citric acid and tripotassium citrate in an
approximately 1*4 molar ratio, respectively, in sufficient pure water to
produce a silver concentration of 100 parts per million. Other
formulations which result in an approximate 1:2 molar ratio to an
approximate 1:20 molar ratio of silver to dibasic citrate in no way
depart from the scope of the invention. Generally, a preferable molar
ratio (as dry ingredient or as solution) of silver to complexing agent is
from about 1:1 to about 1:200, more preferably from about 1:1.5 to 1:50,
most preferably from about 1:2 to about 1:20.
[0028] In another preferable embodiment, the free silver ions are present
in the substantially non-colloidal solution in an anti-microbially
effective amount.
[0029] The inventors have also produced the product following the general
procedures described above but reducing the amounts of citric acid and of
potassium citrate to half of the amounts described above. Numerous other
variations can also be utilized with these starting ingredients provided
that the ratio of citric acid to potassium citrate is generally
maintained. Likewise, the amount of silver oxide may be substantially
increased or decreased provided that a reasonably commensurate adjustment
is made in the relative amounts of citric acid and of potassium citrate
to silver oxide although, as demonstrated by the fact that the product
was successfully produced upon changing the ratio of silver oxide to
citric acid and to potassium citrate by 100%, substantial latitude exists
with regard to that ratio.
[0030] As previously stated herein, numerous alternative source
ingredients for yielding the silver ion, complexing agent, and counter
ion for the preferred embodiment of the invention may also be used,
requiring appropriately adjusted quantities, and, likewise, numerous
other complexing agents and, if required, counter ion agents, may be
selected as the constituents of the product as well, also requiring the
appropriately adjusted quantities of the appropriate source ingredients
necessary to produce the desired product.
[0031] It has often been claimed that ionic silver can kill over 650
disease-causing germs. The invention is absolutely harmless to the body
when used in the low quantities needed for the antimicrobial action to
occur, especially since the formulation provides an efficiently
controlled, gradual release of free silver ions (provided that the
complexing agent is nontoxic), requiring less silver ingestion in order
to obtain the benefits of silver ion activity that other substances
cannot render with substantially higher levels of silver ingestion.
[0032] Ionic silver is used for literally hundreds of conditions,
including eye and ear infections, nose, sinus and gum infections, acne,
sore throats, colds and flu, candida, bladder and vaginal infections,
cuts and burns, many skin conditions, bug bites, fighting nail and skin
fungus, healing sunburn, alleviating diaper rash and bed sores, providing
a soothing skin treatment after shaving, and use as a mouth rinse. Body
odors are caused by bacteria in the perspiration, which is often
alleviated upon application of the invention, clearly demonstrating how
effectively it kills bacteria. Ionic silver is also used for treating
ulcers, both in fighting the bacteria that can aggravate an ulcer and in
repairing the damaged stomach lining. Ionic silver is used for many
severe conditions as well, including, for example, tuberculosis,
Epstein-Barr Virus, Lyme Disease, Legionnaires' Disease, bronchitis,
chicken pox, and numerous others. There are actually few germ-related
conditions, or conditions requiring the repair of tissue, for which ionic
silver is not used, since many claim it is not only effective in killing
most bacteria but also many if not most fungus and viruses. Some reports
indicate that it is also effective against a number of parasites that
might invade the body. Ionic silver is also reported by some researchers
to be effective at treating cancer and HIV.
[0033] Other uses for ionic silver range from purifying bottled water by
placing some in the water, to retardation of food spoilage at home.
Recent studies show that over 30 percent of bottled water contains
bacteria levels above safety limits, which can readily be addressed with
a few drops of the invention being added to the water. Spraying sliced
fruits with the formulation of the invention can keep them fresh up to a
week before spoilage, clearly demonstrating how effectively the invention
kills bacteria on foods. It is also used to reverse existing
contamination of foods.
[0034] Ionic silver is also considered by many to be very useful in oral
irrigation systems designed for consumer use, that spray a fine stream of
water in the mouth, in fighting infection and healing gums. Ionic silver
is even reputed to be quite effective in facilitating the growth of hair
in the local area on which it is topically applied.
[0035] In virtually all applications for which ionic silver is used, the
advantages of a relatively high PPM of silver, a controlled, gradual
release of available free silver ions and, in the case of the preferred
embodiment of the invention, the benefit of citrate as a carrier on
internal use together with the lack of toxicity and minimum likelihood of
incurring mutated strains of germs, all serve to provide substantially
superior benefits to those who would use the product for any of the
myriad of conditions for which ionic silver would be used.
[0036] The product can readily be bottled or packaged with a variety of
types of dispensers to further facilitate its usefulness. A bottle with a
dropper is most convenient for eye drops, ear drops and nose drops.
Alternatively, a plastic squeeze bottle can serve as a convenient
dispenser for eye drops and ear drops, while the same with a nasal
sprayer feature can readily facilitate use as a sinus and nasal spray. A
spray dispenser such as with, for instance, a pump spray, makes it very
convenient to apply the product externally and also provides a convenient
and efficient method for oral use and internal ingestion. By disbursing
the product upon spraying it in the mouth, such a spray facilitates
absorption of the formula into the blood system through the tissue lining
in the mouth. A spray dispenser also facilitates delivery of the product
to the lungs as one may inhale while spraying the product towards the
throat area. while inhaling. Because of the existence of a weak complex
of silver and the existence of available free silver ions, along with the
photoreactive qualities of silver, packaging should preferably be in an
opaque glass container, in a stainless steel container, or in a
polypropylene or polyethylene plastic container. Ideally, dispensers
should be made of such materials as well.
[0037] Topically applying a gauze, cotton, sheer strip or other type of
bandage or fabric that has been saturated with the product is another
alternative for using the product.
[0038] The product can be used for humans as well as animals. When the
complexing agent is a nontoxic material, the product is safe for children
and pets. Thus, the invention has a wide range of potential uses for both
medical and veterinary applications.
[0039] The product can also be applied to surfaces for killing germs
thereon. For instance, it can be sprayed on counter tops, cutting boards,
toilet seats, doorknobs, telephone handsets, etc. Upon contact with germ
cells, the available free silver ions should react with and kill the germ
cell, causing another silver ion to be decomplexed and released from the
complexing agent and be made available.
[0040] The invention may be utilized in both the prevention and the
treatment of disease.
[0041] Due to the efficient delivery of silver ions afforded by the
invention, an individual may ingest the product on a daily basis as a
preventative, achieving substantial levels of protection from germs,
while remaining within extremely safe limits of daily and lifelong silver
intake relative to the amount of silver contained in the product in the
preferred embodiment. Studies show that the amount of silver in the
average daily diet of adult Americans was depleted by as much as 85%
between the early half of the 20th century and the latter part of that
century. With the preferred embodiment of the invention, an individual
consuming a substantial amount of the product on a daily basis in terms
of potential health benefits would, in fact, be consuming no more silver
than that amount which was depleted from the diets over that period of
time.
EXAMPLES
Example 1
[0042] Two and one-half liters of pure water were placed in a 5-gallon (1
9-liter functional capacity) carboy mounted on a magnetic stirrer with a
Teflon-coated magnetic stir bar placed inside the carboy, turning on the
stirrer at low speed, adding 6.7675 grams of citric acid anhydrous powder
(reagent grade), 11.43 grams of potassium citrate monohydrate crystal
(reagent grade), and 2.2450 grams of silver oxide powder (reagent grade),
stirring at low speed for approximately 45 minutes. Next more water was
slowly fed while continuing to stir at low speed for approximately an
additional 15 minutes and stopping the water input when the level reaches
approximately 8-9 liters. Then, the stir speed was turned to high and
stirring continued for approximately an additional 30 minutes, filling
the carboy to approximately the 18-liter mark, turning off the stirrer,
opening the water input valve and stopping the water input at precisely
the 19-liter mark, turning the stirrer back on to the high speed, and
stirring for an additional 60 minutes.
Example 2
[0043] A 65-year old male developed conjunctivitis and obtained relief
within less than five hours upon administering two drops of the solution
of Example 1 in his eye.
Example 3
[0044] A sixteen-year old female had been suffering with acne for three or
four years. A dermatologist had been treating her regularly to no avail.
She applied six sprays of the solution of Example 1 three times per day
to her face for three days and stopped using products from the
dermatologist, and by the end of the third day the skin on her face
cleared up almost completely. There was no dryness or redness any more.
Example 4
[0045] A 45-year old male had been diagnosed with lymphatic cancer and
after taking an oral dose of one teaspoon of the solution of Example 1
per day for two months, tests showed that not a trace of the disease
remained.
Example 5
[0046] A 31-year old male and a 28-year old male who work together in the
same store had both come down with a full-blown flu. Both took fifteen
drops of the solution of Example 1 in an oral dose, one time, and within
a day-and-a-half both were completely free of any further symptoms.
Example 6
[0047] A one-year old male was diagnosed with a blocked tear duct in his
left eye. Every day, he awoke with a green drainage that continued
through the day. Two physicians recommended surgery. The boys mother
administered only one drop of the solution of Example 1 in his eye each
day for two days. The condition disappeared. Upon a follow-up nine months
later, the condition had not returned.
Example 7
[0048] A 53-year old woman burned the back of her hand on a 450-degree
oven. The burn was approximately an inch-and-a-quarter in diameter. After
a week, it still had not begun to heal. The pain was still so bad that
she could barely move her hand. She put two drops of the solution of
Example 1 on it. By that same night, it had completely scabbed over and
the entire circumference of the burn had already generated new tissue.
The pain was completely gone and she had regained complete movement of
her hand. Within about four more days of applying the invention, it was
completely healed, without any scarring.
Example 8
[0049] A 61-year old male had developed a urinary tract infection. A
urologist put him on sulfa drugs for twenty days. He suffered through a
week of constant nausea, at which point he threw out the remaining pills.
He then began to ingest 30 drops of the solution of Example 1 per day,
and after three days the infection was no longer detectable.
Example 9
[0050] A forty-four-year old male developed abscesses surrounding two
wisdom teeth. Three oral surgeons told him the teeth had to come out. He
applied approximately one teaspoon of the solution of Example 1 each to
each of the two affected areas. By the next day, the infections were
undetectable and the pain was gone. A follow-up eleven months later
showed that it had not returned.
Example 10
[0051] A twenty-four-year old woman developed a vaginal infection. The
doctor's prescription didn't help after almost two weeks. She then mixed
one half-teaspoon of the solution of Example 1 in pure water and used the
mixture as a douche, and the discomfort disappeared almost immediately
and had not returned upon a follow-up three weeks later.
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